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Airway

Maximal Airway Response in Adolescents With Long-term Asthma Remission and Persisting Airway Hypersensitivity: Inhaler

In the second phase of study, only the subjects who demonstrated a maximal response plateau were studied. The subjects with asthma remission were randomly allocated into two treatment groups to receive either budesonide (two 200-^g puffs bid; total dosage, 800 ^g/d: budesonide/remission group) or placebo (two 500-^g puffs bid of micronized lactose: placebo/remission group), inhaled […]

Maximal Airway Response in Adolescents With Long-term Asthma Remission and Persisting Airway Hypersensitivity: Materials and Methods

However, for airway hypersensitivity to methacholine in symptom-free and medication-free asthmatic adolescents, neither the presence of maximal response plateau nor the severity of excessive airway narrowing has been investigated so far. This is an important issue because several studies have suggested that the mechanisms underlying maximal airway response and airway sensitivity to methacholine are different, […]